The gankship should be ready on the gate before the AF uses it since the key doesn't hold
Make sure you get every single spawn shooting at you or the gankship WOW Gold will most likely come under heavy fire. It's important that the AF does not crash to desktop or log off while you're doing the complex or for any reason warp out of the complex.
If it does the trip is over and the gankship is probably dead. It's also important that the gankship controls its drones and doesn't aggress anything prematurely. The gankship should be ready on the gate before the AF uses it since the key doesn't hold them open for very long.
That's it. Some modifications might be required for complexes that have tacklers, since the AF will die rather quickly if webified. One can do the Serpentis 10/10 with 2 AFs, or more quickly with AF and a HAC, or even faster with AF, HAC and a BS.
Oh, and don't get too upset when the final overseer can is empty, sometimes you strike it rich with a Nightmare BPC; usually you get some Centum A-Type mods, but you always get 68 million ISK in overseer personal effects from doing the complex plus at least 36 million isk in bounties.
10/10 obviously pays much better since the tags from the first two stages alone pay you more than an entire 6/10 complex in which the final Overseer's can has nothing special.